to determine the effects of Essiac on health-related quality of life (HR-QOL) between women who are new Essiac users (since breast cancer diagnosis) and those who have never used Essiac, with secondary endpoints of differences in depression, anxiety, fatigue, rate of adverse events, and prevalence of complications or benefits associated with Essiac during standard breast cancer treatment found that Essiac does not appear to improve HR-QOL or mood states and seemed to have a negative effect, with Essiac users doing worse than the non-Essiac users.72 This might be attributed to the fact that the group of users comprised younger women with more advanced stages of breast cancer, and both of these subgroups of patients have been shown to be at a significantly increased risk for negative mood states and/or a decreased sense of well-being. By continuing you agree to the use of cookies. Clinical Summary. After 12 weeks of reishi treatment stable disease occurred in 35% of patients, compared to 22% in the control group.50 A palliative effect on cancer-related symptoms, and an increase in Karnofsky performance score occurred in a greater number of patients receiving reishi. Declines in lymphocyte count and/or lymphadenopathy were observed in the majority of patients. Artemisia species demonstrate strong cross-inhibition on immunoblot and ELISA.49. 27-28). No appreciable cross-reactivity exists between these two weeds.47, The order Fagales contains the beech family, Fagaceae; the birch family, Betulaceae; and the walnut family, Juglandaceae. Cancer markers also fell in some patients (see monograph). It seeks open pastures, rocky areas, and … They may be given after conventional treatment for all the above reasons, but also to prevent cancer recurrence and improve survival prospects. (See the turmeric monograph for more details. Sheep's sorrel, Red sorrel, Sour weed, Field sorrel, Acetosella vulgaris. There are countless examples: for example, mild 34°C shock protected fruit fly larvae against a long 0°C shock, mild hypoxia can increase lifespan of the roundworm (Caenorhabditis elegans) and induce cross-tolerance to other types of stress.54, How can exposure to low levels of toxins or other stressors have beneficial effects? [****Celtic Sea Salt is real, evaporated ocean water, which has the perfect blend of minerals, and as such, is not harmful. This favorite culinary herb is rich in antioxidants. The stalks are slender and upright with reddish ridges. 2. There are several books on this topic and a number of systematic reviews and meta-analyses, sometimes by the Cochrane Collaboration. A cohort study (n = 510) by Zick et al. Usual potencies in this range are 6X, 12X (dilution factor of 1 in 10) Or 6C, 30C, 200C, 1M, 10M, 50M AND CM (all based on a dilution factor of 1 in 100). How Rumex Acetosa is effective for various diseases is listed in repertory format. Aviva Romm, in Botanical Medicine for Women's Health, 2010. The sorrels and docks pollinate earlier than many weeds, coinciding with the grass pollen season. However, all generalities are just that, statistical guides for the population as a whole. No peer-reviewed scientific studies have been published regarding the effectiveness of the treatment.71 The topical applications are potentially caustic and damaging to the breast tissue. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780323298759000203, URL: https://www.sciencedirect.com/science/article/pii/B9780443069925000086, URL: https://www.sciencedirect.com/science/article/pii/B978044307277200012X, URL: https://www.sciencedirect.com/science/article/pii/B9780323085939000280, Pediatric Allergy: Principles and Practice (Third Edition), Principles and Practice of Phytotherapy (Second Edition), Immunology and Allergy Clinics of North America. Rumex Acetosella is a plant. The patient was able to complete all six rounds of chemotherapy with normal red and white cell counts at the end. Sheep's Sorrel - Rumex acetosella Edible plant in moderation - novice Other common names Field Sorrel, Lamb Sorrel, Sour Weed, Red Sorrel, Common Sheep Sorrel Scientific name meaning Rumex is derived from the New Latin word Rumicis, which comes for an ancient word for the dock and sorrel family. Birch pollen has distinctive pores with annulus, aspis, and oncus (see Fig. It grows up to 50 Cm. Recently the concept of hormesis has been adopted by biology and medicine as the beneficial adaptive response of cells and organisms to moderate stress. It is a late winter to early spring pollinator. American and Canadian Indian tribes used rumex acetosella as a treatment for cancer, and its use for that disease spread. Pigweeds such as Amaranthus retroflexus are found around the globe (Fig. It is well recognized within the alternative cancer treatment community as one of the ingredients in Essiac tea. All the tested doses of ginger significantly reduced nausea compared with the placebo, and surprisingly the largest reduction occurred for the lower ginger doses (500 mg and 1000 mg). In another study, researchers evaluated the effects of Essiac and another popular herbal product, Flor-Essence, on a line of human breast cancer cells. It also provides substantial amounts of vitamins A, B complex, D, E, and K in addition to beta carotene and the minerals magnesium, phosphorus and potassium. The major pollen allergen Bet v 1 belongs to the pathogenesis-related protein group-10 (PR-10) family and shows strong homology with the group 1 allergens of both Betulaceae and Fagaceae members. The laetrile incident reminds practitioners that cancer patients are notably vulnerable to marketing hype. Apart from the fact that the claim was never adequately tested, it sat uneasily in the alternative culture by competing directly with conventional chemotherapy (see also Chapter 2). Alder pollen has four or five pores, frequently with a squared-off shape (see Fig. Rumex acetosella is the main ingredient in essiac, a popular folk remedy now widely used to treat cancer. Slippery Elm (Ulmus fulva): High is mucilage, this slightly sweet tasting bark has been used for centuries in North America for soothing the digestive tract and absorbing toxins. (See the Boswellia monograph for more details.) A phase II trial in collaboration with the British Columbia Cancer Agency was discontinued apparently because of difficulties in enrolling patients. 27-21). Mugwort (Artemisia vulgaris) in the east and several western sages (Artemisia spp) are important pollen producers in the late summer, rivaling the importance of ragweed in the western states. Sheep sorrell also contains an antibacterial agent called rumicin that has made it a treatment for infections including staphylococcus, E. coli and salmonella. Several open label trials have shown benefit from Boswellia extract in patients with brain tumours in terms of controlling symptoms by reducing inflammation. In a long-term Korean study, the impact of Korean red ginseng (Panax ginseng) therapy on postoperative immunity and survival was investigated in patients with gastric cancer.46 Forty-nine patients who had undergone gastric resection with lymph node removal by the same surgeon for histologically proven AJCC (American Joint Committee on Cancer) stage III gastric adenocarcinoma were enrolled in the trial. After the application of predefined exclusion criteria, 22 patients were given ginseng (4.5 g/day) for the first 6 months after surgery and 20 acted as placebo controls. It is far superior to all competitors; Himalayan salt is a distant second. The latter might include, depending on other indications: Laxatives and cholagogues were often applied where indicated. Quite often, individual herbs or formulations are administered by injection. Best used for Cancer. Species; Additional images; Click here to support NatureSpot by making a donation - small or large - your gift is very much appreciated. Sheep Sorrel (Rumex acetosella)has been a folk remedy for cancer for centuries. The claims for apricot kernels and their constituent ‘laetrile’ or vitamin B17 obscured the fact that this active is a cyanogenic glycoside for which the rationale was in effect a selective toxicity against tumour cells. Although goldenrod and sunflower are primarily insect pollinated, they can release moderate amounts of pollen, which may persist at higher levels as ragweed pollen is waning. This healing herb has diuretic, anti-inflammatory, antiseptic, antimicrobial and antiviral properties. What are the Best Natural Remedies for a Cough? Rumex acetosella, or Sheep sorrel, is a herbaceous perennial herb consisting of a rosette of basal leaves and occasional flowering stalks. The inclusion of Zingiber (ginger) in cases judged to be in need of circulatory stimulation seems to be supported by its status in the NCI rankings. … The women were taking low doses (total daily dose 43.6 ± 30.8 mL) of Essiac that corresponded to the label directions found on most Essiac products. Sun ginseng is a red ginseng extract manufactured under a patented process in Korea. A randomised, placebo-controlled, double blind trial in 53 cancer patients undergoing ‘usual medical treatment’ found that 12 weeks of 3 g/day of sun ginseng significantly improved QOL (p=0.02) and general health (p<0.01).47 A well-publicised study (n=282) on American ginseng root (Panax quinquefolium) found that 750 to 2000 mg/day for 8 weeks significantly reduced cancer-related fatigue.48. Without any clear clinical evidence for this next step, the practitioner can only be guided by precedent. It may have anticancer effects. The subclass Asteridae contains two orders of major allergenic significance: Lamiales and Asterales. Sheep sorrel is a flowering plant considered a perennial weed. It is taken in the form of tea. It is usually administered orally at a dose of 3 g daily in conjunction with chemotherapy, but also with radiotherapy. Sorrel is also found in the proposed herbal cancer remedy, Essiac�, but effectiveness has not been proven. Sheep sorrel has been historically used to treat inflammation, scurvy, cancer, and diarrhea. Nettle (Urtica dioica) is common in Europe and the United States across the floristic zones, with the exception of Florida and the Southeast coastal region, producing large amounts of small, pale, diporate pollen grains and typically underappreciated as a source of hay fever. It is a powerful anti-inflammatory spice … Results have been inconsistent and have required doses than recommended for general consumption to achieve. A 2002 survey of naturopathic physicians in the United States and Canada treating patients with breast cancer reported that the Hoxsey formula was used by 29% of the 161 responders treating localized breast cancer and 24% of the 72 responders treating metastatic breast cancer.70 No toxicity associated with the Hoxsey tonic has been reported, but the potential of toxicity exists from some of its components. This is the most active area of research for phytotherapy in cancer and some relevant clinical studies will be reviewed. It also is high in nutrients. It is also used as a folk medicine to treat cancer and to detoxify the body. However, in gardens especially on sandy, acidic soils it can be a troublesome weed. In North America the theme has been extended into a number of popular approaches to cancer treatment. Perfectly alright in small quantities, the leaves should not be eaten in large amounts since the oxalic acid can lock-up other nutrients in the food, especially calcium, thus causing mineral deficiencies. The closely related chenopod and amaranth weeds of Amaranthaceae are major inducers of hay fever in the later summer. Oak (Quercus), within the beech family, is a major pollen producer with worldwide distribution. Rumex acetosella is commonly used to treat diarrhea. Far safer ground is to use phytotherapy to support the cancer patient undergoing conventional treatments. Gargling with sheep sorrel can clear up mouth ulcers. Rumex Rumex. 27-1). These four major ragweed plants strongly cross-react.27 Cocklebur (Xanthium commune) and the marshelders (Iva spp) are related to ragweed, but are of lesser significance. Phytotherapy may be given prior to conventional treatments to help the patient prepare for them (in order to minimise side effects). A similar formula intended for oral use, without the buckthorn bark and with more cascara sagrada and prickly ash, was listed in the 1926 United States National Formulary (5th ed, 1926) and the 1936 sixth edition as an official remedy known as “Compound Fluidextract of Trifolium,” and was first described in 1898 in the King's American Dispensatory. The allergenically most important is ragweed (Ambrosia), followed by sage (Artemisia). A 2006 systematic review included 19 randomised, controlled studies in 1554 patients receiving antioxidant supplements (not herbal) concurrent with chemotherapy and concluded that there was no evidence for concern, and perhaps benefit.68 A 2008 review that included 16 trials of antioxidants with chemotherapy found the same, but suggested the studies were underpowered.69 The nine radiotherapy studies reviewed suggested less tumour control for vitamin E and beta-carotene. Sheep sorrel (Rumex acetosella) is considered a moderate hay fever inducer, whereas curly or yellow dock (Rumex crispus), although a lower pollen producer, is a common plant. [***Burdock (Arctium Lappa root), Sheep Sorrel (Rumex Acetosella plant), Slippery Elm (Ulmus Rubra bark), Turkey Rhubarb (Rheum Palmatum root).] The pollen grains of the entire family are periporate, with different species having 20 to 100 or more pores over the surface. In uncontrolled trials, reishi extract improved the immune function and stamina of debilitated patients and cancer patients undergoing chemo- and radiotherapies.51 Oral lentinan from Lentinula edodes has improved immune function in cancer patients, although it is usually given by injection for this application.52. Also within Urticaceae is pellitory (Parietaria officinalis), found throughout the North American floristic zones, and which is a major hay fever inducer in the Mediterranean basin. We use cookies to help provide and enhance our service and tailor content and ads. The sorrels and docks pollinate earlier than many weeds, coinciding with the grass pollen season. 27-32). 8) in the 1920s (“Essiac” is Caisse spelled backwards). European medicine also features the specific use of mistletoe extract (notably a product Iscador) as a non-toxic stimulant of endogenous defences (see earlier). So far, so good. Rumex acetosella is a perennial herb that has been used as both food and medicine by many different cultures. Other compelling reasons for using adaptogens as adjunctive therapy are to help the patient survive the treatment, to support immunity and blood cell counts and to assist with well-being and improve QOL. Boswellic acids have inhibited growth of various cancer cells in vitro and in vivo at concentrations of the same order of magnitude to those seen in human pharmacokinetic studies (particularly if Boswellia is taken with food). He was advised to consume button mushrooms, green tea and vegetable juices in his diet and prescribed the following herbal treatments: Four tablets/day of the following formulation:*. The answer lies in the defence molecules the body calls up in response to threats. Chemical components of Rumex acetellosa L. Korean J Pharmacog 1998;29:209-216. 27-20). They usually support their theory with dramatic case reports – encouraging but not entirely persuasive. None of the above can take account of individual differences. It produces dangling catkins and has a long but variable pollen season depending on the species (Fig. People with kidney disorders should avoid the use of sheep sorrel due to its high oxalate content which can cause kidney stones. Willows are widely found in temporal climates and, although primarily insect-pollinated, may release significant amounts of airborne pollen, resulting in sensitization (Figs. Significant improvements in 5-year survival rates in breast, colorectal and gastric cancer have been demonstrated in several controlled clinical trials and in one meta-analysis that included 8009 patients from eight randomised controlled trials.53 However, differences are often relatively modest. The variety of sorrel known as sheep sorrel is one of four ingredients in the herbal cancer … He was about to embark on another six cycles (each over 4 weeks) of a complex intravenous chemotherapy cocktail that included the drugs methotrexate, vinblastine, doxorubicin and cisplatin. Past medical history included testicular cancer 18 years prior that was successfully treated by surgery and chemotherapy. The stems branch at the top and the plant reaches a height of 18 inches. Sorrel’s high vitamin A and C content makes it excellent for the immune system, which means it can possibly benefit cancer, among other immune-based ailments. Tracheophyta › Magnoliopsida › Polygonaceae › Rumex › Rumex acetosella Ecology A rhizomatous perennial herb of dry heaths, non-calcareous sand dunes, shingle beaches and other short, open grasslands on acidic, impoverished, sandy or stony soils. Botanical: Rumex acetosella---Synonym---Field Sorrel. Every part of the plant can be used, but the leaves and roots are most often employed as healing remedies. In April of 1974 Rene Caisse wrote the following to Dr. Chester Stock of Memorial Sloan-Kettering Cancer Center: "The herb that will destroy a cancer is the dog-eared sheep sorrel, sometimes called sourgrass. Description. Supplementation with garlic and green tea seems generally to be advisable. Rumex acetosella, commonly known as red sorrel, sheep's sorrel, field sorrel and sour weed, is a species of flowering plant in the buckwheat family Polygonaceae.Native to Eurasia and the British Isles, the plant and its subspecies are common perennial weeds.It has green arrowhead-shaped leaves and red-tinted deeply ridged stems, and it sprouts from an aggressive and spreading rhizome. It has recently been shown that the stress-protective effect of adaptogens is not the result of inhibition of the stress response of an organism, but actually comes from the adaptation of the organism to the mild stressful effects of the adaptogen. The original formula was developed by the Canadian nurse Rene Caisse (1888-197. The impression from other cultural traditions is that remedies generally considered as eliminatory are those most often used for cancer. Diuretic properties make Rumex acetosella a remedy often used for urinary dysfunction, kidney disorders, and edema. A plant that has been used in some cultures to treat certain medical problems. When combined according to an exact formula, these herbs work together synergistically to detoxify the body and strengthen the immune system. There is substantial preclinical evidence that curcumin targets multiple factors that sustain tumour development and growth.53 Curcumin is currently being trialled (albeit in very high doses) in cancer patients with promising findings. Goldenrod, Solidago spp, is a showy late summer flower which has been blamed for much of the misery caused by the less conspicuous ragweed. The controversial Harry Hoxsey treatments (derived from the formulations of a veterinary practitioner), the Essiac formula (based on sheep sorrel and burdock and supported by more commendations and professional and political support than other natural approaches) and many other examples usually emphasise the same or comparable remedies and themes. The two major tumbleweeds found in the Central Plains, Russian thistle (Salsola kali) and burning bush (Kochia scoparia), are introduced and have expanded throughout the central states to the gulf and California coasts. Cloves. Oak pollen grains are either tricolpate or tricolporate (Fig. Artemisia species, including mugwort (Artemisia vulgaris) in Europe and the eastern states and a number of western sages, are important pollen producers in the late summer, rivaling the importance of ragweed in the western states (Fig. PSK is an isolate rich in polysaccharides from the mushroom Coriolus versicolor approved as an adjunctive cancer treatment in Japan. The use of antioxidants with both chemotherapy and radiotherapy is particularly controversial.65. All the above evidence suggests that in sufferers from cancer it would generally be wise to start supportive treatment with dietary measures to increase fruits, especially citrus fruits and grapes, and vegetables, particularly of the onion, cabbage, umbelliferous and nightshade families and edible fungi. 27-24 and 27-25). Essiac also contains turkey rhubarb, slippery elm and burdock. As a leading cause of global mortality, cancer frequently cannot be cured due to the development of drug resistance. Short (Ambrosia artemisiifolia) and giant (A. trifida) ragweeds predominate in the eastern states through the Central Plains, with false (A. acanthicarpa) and western (A. psilotachya) ragweed common in the Rocky Mountain, Great Basin, Arid Southwest and California Lowlands (Figure 20-2C). Essiac® contains a combination of herbs, including burdock root (Arctium lappa), sheep sorrel (Rumex acetosella), slippery elm inner bark (Ulmus fulva), and Turkish rhubarb (Rheum palmatum). Exposure to the tonics produced a dose-dependent increase in ER activity but did not affect cell proliferation. The former order contains the plantain family, Plantaginaceae, and the olive family, Oleaceae; the latter order includes the largest family of flowering angiosperms, Asteraceae. The order Rosales has several trees and weeds of importance. Essiac also contains turkey rhubarb, slippery elm and burdock. All patients were also treated with chemotherapy each month for 6 months after surgery. Excepting the Florida and Southeast Coastal zones, nettle (Urtica spp) is common. Anti-Cancer - Sheep sorrel is used most famously as an ingredient in Essiac formula for cancer, and the herb has a long history of use in folklore. English dictionary of cancer terms . Botanical name. The repeated administration (adaptation) of adaptogens gives rise to an adaptogenic or stress-protective effect in a manner analogous to repeated physical exercise, leading to a prolonged state of non-specific resistance to stress and increased endurance and stamina under extreme conditions. Sheep Sorrel (Rumex acetosella) is wild, edible and nutritious food. Negative interactions can be either pharmacokinetic or pharmacodynamic, and most evidence for the former exists for extracts of St John’s wort (Hypericum perforatum), probably those rich in hyperforin (see the monograph). A comprehensive two-part review of this topic was published in 2007, which reviewed all published literature from 1965 to 2003.66,67 Most of the concerns expressed were regarding vitamins, and there was little evidence for any negative interaction with herbs. 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