Properly discard this product when it is expired or no longer needed. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. NSAIDs decrease prostaglandin synthesis. Either increases toxicity of the other by pharmacodynamic synergism. NSAIDs decrease prostaglandin synthesis. Serious - Use Alternative (3)ibuprofen and oxaprozin both increase anticoagulation. Modify Therapy/Monitor Closely. These types of antibiotics work slightly better than amoxicillin/potassium clavulanate, cefdinir, and cephalexin. serotonin uptake by platelets. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. oxaprozin and succinylcholine both increase serum potassium. Either increases toxicity of the other by pharmacodynamic synergism. Coadministration may result in a significant decrease in renal function. Comment: May be associated with fluid and electrolyte imbalances. valsartan and oxaprozin both increase serum potassium. Other (see comment). Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.oxaprozin decreases effects of azilsartan by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. For chronic conditions such as arthritis, continue taking it as directed by your doctor. Use Caution/Monitor.Minor (1)indomethacin will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. My husband was soon prescribed it and he also hated it. Coadministration may result in a significant decrease in renal function. Effect of interaction is not clear, use caution. Monitor Closely (3)olmesartan, oxaprozin. Use Caution/Monitor.Minor (1)diflunisal will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Increased risk of GI ulceration. Monitor Closely (1)oxaprozin and sparsentan both increase nephrotoxicity and/or ototoxicity. Effect of interaction is not clear, use caution. Use Caution/Monitor.oxaprozin decreases effects of sotalol by pharmacodynamic antagonism. Minor/Significance Unknown. This information is not individual medical advice and does not substitute for the advice of your health care professional. oxaprozin will increase the level or effect of sulindac by acidic (anionic) drug competition for renal tubular clearance. Both drugs have the potential to cause bleeding, monitor closely. Monitor Closely (1)perindopril, oxaprozin. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. labetalol and oxaprozin both increase serum potassium. Modify Therapy/Monitor Closely. Monitor Closely (1)oxaprozin increases and epinephrine racemic decreases serum potassium. pharmacodynamic antagonism. Monitor Closely (1)latanoprostene bunod ophthalmic, oxaprozin. Keep all medical and lab appointments. NSAIDs decrease prostaglandin synthesis. sotalol and oxaprozin both increase serum potassium. Use Caution/Monitor. Use Caution/Monitor.oxaprozin decreases effects of bisoprolol by pharmacodynamic antagonism. meclofenamate and oxaprozin both increase anticoagulation. propranolol and oxaprozin both increase serum potassium. Use Caution/Monitor. Modify Therapy/Monitor Closely. Do not use Daypro just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Effect of interaction is not clear, use caution. Either increases toxicity of the other by pharmacodynamic synergism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Use Caution/Monitor. oxaprozin decreases effects of sacubitril/valsartan by pharmacodynamic antagonism. oxaprozin increases levels of lithium by decreasing renal clearance. Effect of interaction is not clear, use caution. Increased risk of bleeding events. Long term (>1 wk) NSAID use. oxaprozin and salsalate both increase serum potassium. NSAIDs decrease prostaglandin synthesis. Effect of interaction is not clear, use caution. oxaprozin increases effects of tolbutamide by unknown mechanism. Either increases levels of the other by plasma protein binding competition. Oxaprozin is known as a nonsteroidal anti-inflammatory drug (NSAID).If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others.Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as celecoxib, ibuprofen, ketorolac). Comment: Risk of acute renal failure. Tell your doctor if you are pregnant or if you plan to become pregnant. Either increases levels of the other by plasma protein binding competition. Do not store in the bathroom. Use Caution/Monitor.oxaprozin and salsalate both increase serum potassium. Minor/Significance Unknown. Either increases toxicity of the other by pharmacodynamic synergism. oxaprozin increases levels of pralatrexate by decreasing renal clearance. Increased risk of upper GI bleeding. Most Other (see comment). Mobic has active ingredients of meloxicam. Minor/Significance Unknown. Use Caution/Monitor.ketorolac and oxaprozin both increase serum potassium. Either increases effects of the other by anticoagulation. Monitor Closely (2)oxaprozin decreases effects of celiprolol by pharmacodynamic antagonism. Minor/Significance Unknown. Minor/Significance Unknown. Long term (>1 wk) NSAID use. antiplatelet effects. escitalopram, oxaprozin. Effect of interaction is not clear, use caution. provider for the most current information. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. tobramycin inhaled and oxaprozin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. venlafaxine, oxaprozin. Created for people with ongoing healthcare needs but benefits everyone. Use Caution/Monitor.Minor (1)aceclofenac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Bleeding risk may be increased when NSAIDs are used concomitantly with rivaroxaban. oxaprozin and forskolin both increase anticoagulation. Either increases effects of the other by pharmacodynamic synergism. There are five classes of antidepressant: Selective serotonin reuptake inhibitors (SSRIs): Prozac (fluoxetine), Zoloft (sertraline), Celexa (citalopram), and Lexapro (escitalopram), and others. TYLER J. RAYMOND, DO, MPH, FAAFP, KRISTEN A. TOBIN, MD, AND TYLER S. ROGERS, MD, FAAFP, Madigan Army Medical Center, Tacoma, Washington. oxaprozin will increase the level or effect of salicylates (non-asa) by acidic (anionic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. Mean pain duration was 7.9 years, with a mean pain severity of 6 out of 10. Use Caution/Monitor. This is a decision you and your doctor will make. pharmacodynamic antagonism. Increased risk of upper GI bleeding. NSAIDs decrease prostaglandin synthesis, increasing the risk of nephrotoxicity. oxaprozin, triamcinolone acetonide injectable suspension. This risk is likely greatest in patients who have a prior history of CVD or . meclofenamate will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. NSAIDs resulted in small improvements in pain and function in the short term, particularly in patients with knee pain and those with higher baseline pain severity. Avoid or Use Alternate Drug. pharmacodynamic antagonism. unspecified interaction mechanism. Use Caution/Monitor. Use Caution/Monitor.Minor (1)oxaprozin will increase the level or effect of choline magnesium trisalicylate by acidic (anionic) drug competition for renal tubular clearance. mefenamic acid and oxaprozin both increase serum potassium. Minor/Significance Unknown. oxaprozin increases levels of methotrexate by decreasing renal clearance. AHRQs summary is accompanied by an interpretation by an AFP author that will help guide clinicians in making treatment decisions. All rights reserved. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Meloxicam is considered a strong Motrin, but this meloxicam knocked me out for 24 hours. Use Caution/Monitor. Other (see comment). Effect of interaction is not clear, use caution. Minor/Significance Unknown. The Agency for Healthcare Research and Quality (AHRQ) review focused on seven common chronic pain conditions (neuropathic pain, fibromyalgia, osteoarthritis, inflammatory arthritis, low back pain, chronic headache, and sickle cell disease) and assessed the effectiveness of common nonopioid medications on the primary outcomes of pain, function, and quality of life, as well as adverse events related to these medications. naproxen will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Monitor Closely (1)levomilnacipran, oxaprozin. Minor/Significance Unknown. esmolol and oxaprozin both increase serum potassium. eHealthMe is studying from 2,834 Daypro users for its effectiveness, alternative drugs and more. nephropathy. Minor/Significance Unknown. Individual plans may vary serotonin uptake by platelets. Use Caution/Monitor. Monitor Closely (1)oxaprozin, vorapaxar. triamterene and oxaprozin both increase serum potassium. NSAIDs decrease prostaglandin synthesis. Minor/Significance Unknown. cefpirome will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Daypro (oxaprozin) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the signs and symptoms of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor.Serious - Use Alternative (1)oxaprozin, ketorolac. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.valsartan, oxaprozin. clomipramine, oxaprozin. oxaprozin and sulfasalazine both increase anticoagulation. Either increases toxicity of the other by pharmacodynamic synergism. oxaprozin increases and bumetanide decreases serum potassium. Use Caution/Monitor. Use Caution/Monitor. Increased risk of upper GI bleeding. 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